"I have Democrat friends and Republican friends. I get along with almost everyone, but I have never worked with a more miserable son of a bitch in my life," said Former House Speaker John Boehner told the history professor emeritus at Stanford.
"Lucifer in the flesh," replied Boehner. A response that's already garnered attacks from the senator.
"John Boehner's remarks reveal everything that's wrong and corrupt about Washington, everything you're angry with."
"When John Boehner calls me Lucifer, he's not directing that at me. He's directing it at you," Cruz said.
Last year, while Ted Cruz led the rogue effort to secure a government shutdown, Boehner called the senator a "jackass" and "false prophet."
In many ways, Ted Cruz remains one of the few politicians committed to the Tea Party faction, since many other senators dismissed the movement after midterm elections.
Despite the animosity between Ted and Congress, the former outsider may find more in common with the establishment conservatives by the GOP convention.
Whether or not Cruz falls in line, it is still clear the Texas senator lost his chance to run as an political outsider after Donald Trump continues to take the conservative establishment by surprise.
As they say, "Politics makes strange bedfellows."